Glimepiride Tablets IP 4 mg are oral antidiabetic tablets used in the treatment of type 2 diabetes mellitus. Glimepiride is a second-generation sulfonylurea that lowers blood sugar by stimulating insulin release from the pancreas and improving insulin sensitivity in peripheral tissues. It is typically prescribed once daily, preferably with breakfast or the first main meal, and may be used alone or in combination with other antidiabetic medications. Glimepiride offers effective blood glucose control but requires monitoring to avoid hypoglycemia, especially in elderly patients or those with kidney or liver impairment.