Pancreatin Minimicrospheres Capsules are enzyme-replacement capsules used to treat exocrine pancreatic insufficiency (EPI) caused by conditions like cystic fibrosis, chronic pancreatitis, or pancreatic surgery. Each capsule contains minimicrospheres of lipase, amylase, and protease, which help digest fats, carbohydrates, and proteins. The enteric-coated microspheres protect the enzymes from stomach acid and release them in the small intestine for optimal absorption.