Ofloxacin, Dexamethasone, and Hydroxypropylmethylcellulose (HPMC) ear/eye drops combination treats bacterial infections with associated inflammation and dryness. Ofloxacin is a broad-spectrum fluoroquinolone antibiotic that kills bacteria by inhibiting DNA replication enzymes. Dexamethasone is a corticosteroid that reduces inflammation, redness, and swelling. HPMC acts as a lubricant, improving comfort and extending the retention time of the active ingredients on the eye surface. This combination is commonly used to manage conditions like bacterial conjunctivitis, blepharitis, keratitis, otitis externa, and post-surgical inflammation in both eyes and ears.