Gatifloxacin eye drops are a sterile ophthalmic solution containing a fourth-generation fluoroquinolone antibiotic that treats bacterial infections of the eye. It works by inhibiting bacterial enzymes essential for DNA replication, effectively killing a broad range of gram-positive and gram-negative bacteria. The drops are commonly used to manage conditions such as bacterial conjunctivitis, keratitis, blepharitis, and to prevent infections following eye surgery or trauma.