Description
We offer Loteprednol Etabonate Ophthalmic Suspension 0.5%, a corticosteroid eye drop used to treat inflammation and pain caused by ocular conditions such as allergic conjunctivitis, post-operative swelling, and anterior uveitis. This topical ophthalmic steroid is formulated for minimal systemic absorption, reducing the risk of long-term side effects.
Product Details:
- Composition: Loteprednol Etabonate 0.5% w/v
- Form: White to off-white sterile ophthalmic suspension
- Packaging: 5 mL plastic dropper bottle
- Application: Anti-inflammatory eye medication
- Shelf Life: 24 months
Key Features:
- Treats post-operative eye inflammation and pain
- Effective for allergic conjunctivitis, anterior uveitis, and seasonal eye irritation
- Fast-acting with reduced risk of intraocular pressure rise
Mechanism of Action – Loteprednol Etabonate
- Anti-inflammatory Effect (Main Action): Loteprednol etabonate binds to glucocorticoid receptors in cells and Inhibits the release of pro-inflammatory mediators like prostaglandins and leukotrienes. Also suppresses the activity of phospholipase Ad n2, reducing arachidonic acid release, which is a key step in inflammation.
- Localized Effect with Minimal Systemic absorption: Unlike other corticosteroids, loteprednol is an ester-based steroid (not a ketone), which is designed to be rapidly metabolized into inactive forms, reducing systemic side effects. Also Helps maintain low intraocular pressure (IOP) compared to traditional steroids like dexamethasone or prednisolone.
