Description
Ketoconazole Cream 2% w/w is a broad-spectrum antifungal cream used to treat a range of fungal and yeast infections of the skin, including ringworm, jock itch, athlete’s foot, and seborrheic dermatitis. It works by disrupting the fungal cell membrane, effectively eliminating the infection.
Mechanism of Action:
Ketoconazole is an imidazole antifungal that works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. Without ergosterol, the cell membrane becomes damaged, leading to leakage of cell contents and eventual fungal cell death. It also has some anti-inflammatory activity, which can help relieve itching and redness.
Uses:
Ketoconazole Cream 2% is used to treat a variety of superficial fungal infections, including:
- Tinea corporis (ringworm of the body)
- Tinea cruris (jock itch)
- Tinea pedis (athlete’s foot)
- Tinea versicolor (pityriasis versicolor)
- Cutaneous candidiasis (yeast infections of the skin)\
- Seborrheic dermatitis (fungal-related skin condition with dandruff, redness, or itching)
