Description
Amlodipine works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle. This leads to vasodilation, reduced peripheral resistance, and subsequently lower blood pressure.
- IUPAC Name: 3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
- Molecular Formula: C20H25ClN2O5
- Molecular Weight: 408.88 g/mol
- Therapeutic Class: Calcium channel blocker (dihydropyridine class)
- Usage: Primarily used to treat hypertension (high blood pressure) and angina (chest pain).
- Appearance: White to off-white crystalline powder
- Solubility: Sparingly soluble in water; soluble in methanol and ethanol
- Melting Point: 199–201°C
- Optical Rotation: Slightly optically active (due to chirality in the molecule)
- Stability: Stable under recommended storage conditions (cool, dry place, protected from light)
- Packaging and Storage:
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Packaging: HDPE drums or fiber drums with double PE liners
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Standard Pack Sizes: 5kg / 10 kg/ 25kg
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Storage Conditions: Store below 25°C, in a dry place, away from light and moisture
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